ScorpDb

Scorpion and Scorpion venom peptides Database


Interesting and important recent scorpion papers are listed in this page:

-Adame, M., Vázquez, H., Juárez-López, D., Corzo, G., Amezcua, M., López, D., González, Z., Schcolnik-Cabrera, A, Morales-Martínez, A., 2024. Villegas E. Expression and characterization of scFv-6009FV in Pichia pastoris with improved ability to neutralize the neurotoxin Cn2 from Centruroides noxius. Int J Biol Macromol. Aug, 275(Pt 1):133461.

-Ajdi, B., El Asbahani, A., El Hidan, M.A., Bocquet, M., Falconnet, L., Hamza, M.A., Elmourid, A., Touloun, O.,  Boubaker, H.,  Bulet, P., 2024. Molecular diversity assessed by MALDI mass spectrometry of two scorpion species venom from two different locations in Morocco. Toxicon, 238:107562.

-Baradaran, M., Salabi, F., 2023. Genome-wide identification, structural homology analysis, and evolutionary diversification of the phospholipase D gene family in the venom gland of three scorpion species. BMC Genomics. 24:730.

-Borges, A., Lomonte, B., 2024. Proteomic analysis and lethality of the venom of Aegaeobuthus nigrocinctus, a scorpion of medical significance in the Middle East. Acta Tropica, 255: 107230.

-Díaz, C., Lomonte, B., Chang-Castillo, A., Bonilla, F., Alfaro-Chinchilla, A., Triana, F., Angulo, D., Fernández, J., Sasa, M., 2024. Venomics of Scorpion Ananteris platnicki (Lourenço, 1993), a New World Buthid That Inhabits Costa Rica and Panama. Toxins (Basel). Jul 23;16(8):327.

-Fong-Coronado, P.A., Ramirez, V., Quintero-Hernández, V., Balleza, D., 2024. A Critical Review of Short Antimicrobial Peptides from Scorpion Venoms, Their Physicochemical Attributes, and Potential for the Development of New Drugs. The Journal of Membrane Biology, 257, 165–205.

-Gunas, V., Maievskyi, O., Raksha, N., Vovk, T., Savchuk, O., Shchypanskyi, S., Gunas, I., 2023. Protein and peptide profiles of rats’ organs in scorpion envenomation. Toxicology Reports, 10, 615–620.

-Gunas, V., Maievskyi, O., Synelnyk, T., Raksha, N., Vovk, T., Halenova, T., Savchuk, O., Gunas, I., 2024. Cytokines and their regulators in rat lung following scorpion envenomation. Toxicon X, 22, 100198.

-Hernández-Muñoz, E.A., Zavala-Sánchez, E.V., 2024. Scorpion sting envenomation: should it be considered a neglected tropical disease? International Journal of Epidemiology, 53(3), dyae070.

-Kazemi, S. M., Gholam Kelisani, Z., Avella, I., Luddecke, T., 2024. The need for a refined scorpion antivenom for Iran. Toxicon, 248, 108033.

-Kuzmenkov, A.I., Gigolaev, A.M., Pinheiro-Junior, E.L., Peigneur, S., Tytgat, J., Vassilevski, A.A., 2023. Methionine-isoleucine dichotomy at a key position in scorpion toxins inhibiting voltage-gated potassium channels. Toxicon, 231, 107181.

-López-Giraldo, E., Carrillo, E., Titaux-Delgado, G., Cano-Sánchez, P., Colorado, A., Possani, L.D., del Río-Portilla, F., 2023. Structural and functional studies of scorpine: A channel blocker and cytolytic peptide. Toxicon, 222, 106985.

-Mabunda, IG., Zinyemba, NK., Pillay S., Offor, BC., Muller, B., Piater, LA., 2024. The geographical distribution of scorpions, implication of venom toxins, envenomation, and potential therapeutics in Southern and Northern Africa. Toxicol Res (Camb). 4;13(4):tfae118.

-Mendes, L.C., Viana, G.M.M.,Nencioni, A.L.A., Pimenta, D.C., Beraldo-Neto, E., 2023. Scorpion Peptides and Ion Channels: An Insightful Review of Mechanisms and Drug Development. Toxins, 15, 238.

-Nasr, S., Borges, A., Sahyoun, C., Nasr, R., Roufayel, R., Legros, C., Sabatier, J.-M., Fajloun, Z., 2023. Scorpion Venom as a Source of Antimicrobial Peptides: Overview of Biomolecule Separation, Analysis and Characterization Methods. Antibiotics, 12, 1380.

-Panayi, T., Diavoli, S., Nicolaidou, V., Papaneophytou, C., Petrou, C., Sarigiannis, Y., 2024. ShortChained Linear Scorpion Peptides: A Pool for Novel Antimicrobials. Antibiotics, 13, 422.

-Pashmforoosh, N. Baradaran, M., 2023. Peptides with Diverse Functions from Scorpion Venom: A Great Opportunity for the Treatment of a Wide Variety of Diseases. Iranian Biomedical Journal, 27, 84–99.

-Peter Muiruri, K., Zhong, J., Yao, B., Lai, R., Luo, L., 2023. Bioactive peptides from scorpion venoms: therapeutic scaffolds and pharmacological tools. Chinese Journal of Natural Medicines, 21(1):19-35.

-Qin, C., Yang, X., Zuo, Z., Yuan, P., Sun, F., Luo, X., Ye, X., Cao, Z., Chen, Z., Wu, Y.,2024. Differential potassium channel inhibitory activities of a novel thermostable degradation peptide BmKcug1a-P1 from scorpion medicinal material and its N-terminal truncated/restored peptides. Sci Rep. 12;14(1):16092.

-Ramanan da Cruz, J., Bulet, P., Mendonça de Moraes, C., 2024. Exploring the potential of Brazilian Amazonian scorpion venoms: A comprehensive review of research from 2001 to 2021. Toxicon X, 21, 100182.

-Rivera-de-Torre, E., Lampadariou, S., Møiniche, M., Bohn, M.F., Kazemi, S.M., Laustsen, A.H., 2024. Discovery of broadly-neutralizing antibodies against brown recluse spider and Gadim scorpion sphingomyelinases using consensus toxins as antigens. Protein Science, 33 (3), e4901.

-Salabi, F., Vazirianzadeh, B., Baradaran, M., 2023. Identification, classification, and characterization of alpha and beta subunits of LVP1 protein from the venom gland of four Iranian scorpion species. Scientific reports. 13:22277.

-Wang, X., Luo, H., Peng, X., Chen, J., 2024. Spider and scorpion knottins targeting voltage-gated sodium ion channels in pain signaling. Biochem Pharmacol. Epub 2024 Aug 3. PMID: 39102991

-Wang, K., Nguyen, T., Gao, Y., Guo, R., Fan, C., Liao, H., Li, J., Chai, J., Xu, X., Gong, Y., Chen, X., 2024. Androcin 18-1, a novel scorpion-venom peptide, shows a potent antitumor activity against human U87 cells via inducing mitochondrial dysfunction. Insect Biochem Mol Biol. Epub 2024 May 15. PMID: 38759703.

-Xia, Z., He, D., Wu, Y., Kwok, H.F., Cao, Z., 2023. Scorpion venom peptides: Molecular diversity, structural characteristics, and therapeutic use from channelopathies to viral infections and cancers. Pharmacological Research,197:106978.

-Xia, Z., Wang, H., Chen, W., Wang, A., Cao, Z., 2024. Scorpion Venom Antimicrobial Peptide Derivative BmKn2-T5 Inhibits Enterovirus 71 in the Early Stages of the Viral Life Cycle In Vitro. Biomolecules, 14, 545.

-Yamashita, T., Rhoads, DD., Pummill, J., 2024. A robust genome assembly with transcriptomic data from the striped bark scorpion, Centruroides vittatus. G3 (Bethesda). 7;14(8):jkae120.

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Scorpion photos of the main page by Dr. Masoumeh Baradaran, Dr. Fatemeh Salabi, Dr. Ahmad Ghorbani, and Mohammad Hossein Jahan-Mahin
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